色中色 (PCOM) has been awarded a $5.5 million contract from the Patient-Centered Outcomes Research Institute (PCORI) to study the effectiveness of psychosocial treatments for individuals receiving medication assisted treatment (MAT) for opioid use disorder (OUD) at four federally qualified health centers. The study will examine the effectiveness of two psychosocial treatments 鈥� cognitive behavioral therapy (CBT) and peer recovery support 鈥� individually and in combination.
鈥淧sychosocial treatments including CBT and peer support have shown great promise in
treating addictive disorders, but have not been extensively studied in combination
with MAT for OUD,鈥� said David Festinger, PhD, director of substance abuse research and education at PCOM, and the study鈥檚 principal
investigator (PI).
鈥淢oreover, there is no one-size-fits-all approach to treating opioid addiction, just as there is no one-size-fits-all approach to treating any other disease,鈥� he added. 鈥淭his study will help to determine which psychosocial approach works best for different types of patients, allowing us to tailor treatment more effectively.鈥�
The project will follow 440 patients receiving buprenorphine/naloxone, a partial opioid antagonist, randomized into one of four conditions: (1) Medication alone, (2) Medication with CBT, (3) Medication with peer support, or (4) Medication with CBT and peer support. Study outcomes will include opioid abstinence, treatment retention, quality of life and emergency hospitalizations.
鈥淭his program of research will examine the utility of a multidisciplinary approach
to treating this major public health crisis,鈥� said Michelle Lent, PhD, associate professor, clinical psychology and co-investigator. 鈥淲e are finding that even the most promising pharmaceutical
treatments benefit from behavioral strategies to promote adherence and sustain positive
health outcomes.鈥�
鈥淭his project was selected for PCORI funding not only for its scientific merit and commitment to engaging patients and other healthcare stakeholders in a major study conducted in real-world settings, but also for its potential to answer an important question about the treatment of opioid addiction and fill a crucial evidence gap,鈥� said PCORI Executive Director Joe Selby, MD, MPH. 鈥淲e look forward to following the study鈥檚 progress and working with PCOM to share its results.鈥�
The study was selected through a highly competitive review process in which patients, caregivers and other stakeholders joined scientists to evaluate the proposals. The study is expected to begin enrollment in spring of 2020.
PCORI is an independent, nonprofit organization authorized by Congress in 2010. Its mission is to fund research that will provide patients, their caregivers and clinicians with the evidence-based information needed to make better-informed healthcare decisions. For more information about PCORI鈥檚 funding, visit .
Established in 1899, 色中色 (PCOM) has trained thousands of highly competent, caring physicians, health practitioners and behavioral scientists who practice a 鈥渨hole person鈥� approach to care鈥攖reating people, not just symptoms. PCOM, a private, not-for-profit accredited institution of higher education, operates three campuses (PCOM, PCOM Georgia and PCOM South Georgia) and offers doctoral degrees in clinical psychology, educational psychology, osteopathic medicine, pharmacy, physical therapy, and school psychology. The college also offers graduate degrees in applied behavior analysis, applied positive psychology, biomedical sciences, forensic medicine, medical laboratory science, mental health counseling, physician assistant studies, and school psychology. PCOM students learn the importance of health promotion, research, education and service to the community. Through its community-based Healthcare Centers, PCOM provides care to medically underserved populations. For more information, visit pcom.edu or call 215-871-6100.
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